منابع مشابه
Clathrin Adaptors Really Adapt
The clathrin pathway is the principal route for receptor-mediated endocytosis and growth factor downregulation. Heterotetrameric clathrin adaptors directly link the clathrin coat with cargo transmembrane proteins that are sorted into coated pits and vesicles. A paper in this issue of Cell describes the atomic structure of the adaptor-protein 2 (AP-2) core, the portion that makes contacts with t...
متن کاملMinireviewClathrin Adaptors Really Adapt
proteins into clathrin pathways. Because of their key The clathrin pathway is the principal route for receprole in linking sorted proteins with the clathrin coat, the tor-mediated endocytosis and growth factor downregassembly factors are now referred to as heterotetramulation. Heterotetrameric clathrin adaptors directly eric clathrin adaptors. link the clathrin coat with cargo transmembrane pro...
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The essence of architectural styles is component communication. In this paper, we relate architectural styles to adaptors in the GenVoca model of software construction. GenVoca components are refinements that have a wide range of implementations, from binaries to rule-sets of program transformation systems. We explain that architectural styles can (1) be understood as refinements (like other Ge...
متن کاملAdaptors, junction dynamics, and spermatogenesis.
Adaptors are component proteins of junctional complexes in all epithelia, including the seminiferous epithelium of the mammalian testis. They recruit other regulatory and structural proteins to the site of both anchoring junctions (such as cell-cell actin-based adherens junctions [AJs], e.g., ectoplasmic specialization [ES] and tubulobulbar complex, which are both testis-specific cell-cell acti...
متن کاملAdaptors for clathrin-mediated traffic.
Clathrin-based systems are responsible for a large portion of vesicular traffic originating from the plasma membrane and the trans-Golgi network that reaches the endosomal compartment. The assembly of cytosolic clathrin forms the scaffold required for the local deformation of the membrane and for the formation of coated pits and vesicles. In this process, clathrin interacts in a coordinated fas...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2002
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn864